Infectious Disease Compendium

Zoliflodacin

Dosing

CrCl Formula

3 gm po.

Important side effects

Important drug interactions

Rants and Screeds

Pearls

Treatment of choice

Use for

Uncomplicated urogenital and rectal gonococcal infections. Pharyngeal not so much. In clinical trials.

Don't use for

Class

Spiropyrimidinetrione. It "inhibits microbial biosynthesis by arresting the cleaved covalent gyrase complex and the formation of fused circular DNA required for biosynthesis (PubMed)."

Last update 04/04/20