CrCl > 80: 900 mg po bid for induction, 900 qd for prevention and maintenance.
CrCl < 10:
Important side effects
Abdominal pain, diarrhea, nausea, vomiting, anemia, neutropenia (very common), thrombocytopenia, headache, insomnia.
Important drug interactions
Rants and Screeds
I would avoid where absorbtion may be an issue, such as colitis.
Treatment of choice
CMV retinitis. Perhaps other manifestations of CMV, it achieves blood levels nearly as good as iv.