Infectious Disease Compendium

Telavancin (Vibativ)

Dosing

CrCl Formula

CrCl > 50: 10 mg/kg every 24 h.

Important side effects

Mild taste disturbance (a tendency to wear bell bottoms?), nausea, vomiting, serum creatinine concentration elevation.

Important drug interactions

Rants and Screeds

Pearls

Treatment of choice

Use for

Gram postive organisms, including MRSA. It is equal to vancomycin (and therefore a piece of crap) for cellulitis and hospital acquired pneumonia (pneumonia cure rates with telavancin versus vancomycin were 58.9% versus 59.5%. Ick.) (PubMed).

Don't use for

Class

Lipoglycopeptide.