Infectious Disease Compendium

Telaprevir (Incivek)

Dosing

CrCl Formula

CrCl > 80: 750 mg every 8 hours.

Important side effects

Fatigue, pruritus, rash, nausea,influenza-like illness, anemia, and diarrhea.

Important drug interactions

Rants and Screeds

Pearls

Treatment of choice

Use for

Hepatitis C retreatment (PubMed). Genotype 1 chronic hepatitis C.

Don't use for

Class

 Inhibits the hepatitis C virus serine protease.