Infectious Disease Compendium

Rimantadine (Flumadine®)


CrCl Formula

CrCl > 80: 100 mg po bid.

Important side effects

Anorexia, dry mouth, nausea, vomiting, dizziness, insomnia, nervousness, increased seizure activity in patients with seizures.

Important drug interactions

Rants and Screeds


Less neurotoxic in the elderly than amantadine.

Treatment of choice

Use for

Influenza A (92% of influenza A is now resistant to amantadine and rimantadine; use zanamivir or olsatamivir).

Don't use for

Not influenza B. That's NOT B. B BBBBBBBBBB.


M2 pump inhibitor that prevents viral uncoating.