Infectious Disease Compendium

Rifaximin (Lumenax®)

Dosing

CrCl Formula

CrCl > 80: 200 mg three times daily for three days.

Important side effects

Constipation, headache, vomiting.

Important drug interactions

Rants and Screeds

Pearls

Shortens the duration of diarrhea by 27 hours. Precisely 27 hours. That is precision without accuracy.

Treatment of choice

Use for

Bacterial diarrhea; including Clostridiu difficile and travelers diarrhea. It has no absorption.

Still, it breeds rifampin resistance in Staphylococcus aureus (PubMed).

Don't use for

Campylobacter jejuni.

Class