Infectious Disease Compendium

Rifapentine

Dosing

CrCl Formula

CrCl > 80: 600 mg po q week with INH. Used when sputum converts to AFB negative after two months of INH and Rifampin.

Important side effects

Hepatitis and thrombocytopenia. Like rifampin.

Important drug interactions

p450 inducer. Like rifampin.

Rants and Screeds

Pearls

Treatment of choice

Use for

Tuberculosis.

Don't use for

Children, HIV.

Class

Rifamycin.