CrCl > 80: 400 mg bid. If patients on rifampin the dose is 800 bid.
Important side effects
Low WBC, increase in transaminases and CK. Rash.
There is an association with HLA-B*53:01 and Drug Reaction With Eosinophilia and Systemic Symptoms (DRESS) Syndrome (PubMed) Or should it be called DRESSS?>
Important drug interactions
Rants and Screeds
Treatment of choice
Don't use for
Integrase inhibitor. Popular with Strom Thurman and George Wallace.