Infectious Disease Compendium

Proguanil (Paludrine®)

Dosing

CrCl Formula

CrCl > 80: 400 mg po qd. When combined with atovaquone it is Malarone®).

Important side effects

Cytopenias, mouth ulcers, rash.

Important drug interactions

Aurothioglucose, chloroquine, warfarin.

Rants and Screeds

Pearls

Treatment of choice

Use for

Resistant malaria prophylaxis and treatment (combined with atovaquone).

Don't use for

Class