Infectious Disease Compendium

Praziquantel (Biltricide®)

Dosing

CrCl Formula

CrCl > 80: 20-25 mg/kg/day (600 mg tablets) Dose and duration depend on infection.

CrCl 80-50:

CrCl 50-10:

CrCl < 10:

Hemodialysis:

Peritoneal dialysis:

Important side effects

Abdominal pain, arrhythmias, heart block, convulsions, dizziness, headache, malaise.

Important drug interactions

Albendazole, carbamazepine, chloroquine, cimetidine, fosphenytoin, phenytoin.

Rants and Screeds

Way expensive.

Pearls

This is not an Aztec god. But it sure sounds like one.

Treatment of choice

Cystercercosis, Schistosomiasis.

Use for

Clonorchis sinensis /opisthorchiasis, Cystercercosis, Diphyllobothrium infections, Echinococcus granulosus infections, Fasciolopsis buski, Heterophyes heterophyes,, Hymenolepis nana infections, Metagonimus yokogawai infection, Nanophyetiasis, Paragonimiasis, Schistosomiasis, Taenia saginata, Taenia solium.

Don't use for

Class