Infectious Disease Compendium

Piperazine

Dosing

CrCl Formula

CrCl > 80: 150 mg/kg initially, then 6 doses of 65 mg/kg q 12 h.

Important side effects

Neurologic sx of all kinds(cerebellar ataxia, coma, dementia, headache, lethargy, movement disorder, muscle weakness, paresthesia, psychiatric findings, seizures, vertigo).

Important drug interactions

Rants and Screeds

Pearls

Paralyzes the worm and relieves gi obstruction. So warn the patient they will pass whole worms. Ick.

Treatment of choice

Use for

A. lumbricoides.

Don't use for

Class