Infectious Disease Compendium

Penicillin VK

Dosing

CrCl Formula

CrCl > 80: 500 mg po q 6 h.

CrCl 80-50:

CrCl 50-10:

CrCl < 10:

Hemodialysis:

Peritoneal dialysis:

Important side effects

Immune mediated cytopenias, allergic reactions, eosinophilia, hemolytic anemia, interstitial nephritis.

Important drug interactions

Chloramphenicol, cholestyramine, ethinyl estradiol, mestranol, methotrexate, norelgestromin, norethindrone, norgestrel.

Rants and Screeds

Pearls

Treatment of choice

Use for

Streptococci. Animal bites, Cellulitis, dental Endocarditis prophylaxis, Lyme Disease necrotizing ulcerative gingivitis, Human bites, Otitis media, Pharyngitis, Rheumatic Fever prophylaxis, scarlet fever, strep throat, Streptococcus pneumoniae infections, Streptococcus pyogenes, trench mouth, Vincent's infection.

Don't use for

Class

Hmmmmmm.