Infectious Disease Compendium

Minocycline

Dosing

CrCl Formula

CrCl > 80: 200 mg, then 100 mg q12h.

CrCl 80-50:

CrCl 50-10:

CrCl < 10:

Hemodialysis:

Peritoneal dialysis:

Important side effects

Dizziness, light-headedness, vertigo.

Important drug interactions

Acitretin, aluminum, calcium or magnesium containing products, bismuth subsalicylate, cisatracurium, dicumarol, ethinyl estradiol, iron, isotretinoin, levonorgestrel, mestranol, norethindrone, norgestrel, porfimer, rapacuronium, vitamin a, warfarin.

Rants and Screeds

Pearls

Treatment of choice

Use for

Acne, Amebiasis, Anthrax, Bacillary angiomatosis, balnei infections, Bronchitis, Cellulitis, Conjunctivitis, Cystic fibrosis, eosinophilic cellulitis, gingival inflammation, Gonorrhea, Leprosy, Malaria, Neisseria meningitidis, non-gonococcal Urethritis, papillomatosis, Pneumonia, Prostatitis, pulmonary Nocardia, pyoderma gangrenosum, Q fever, Reiter's syndrome (yes I know he was a Nazi and I should not use his name), rheumatoid arthritis, Rickettsia infections, rickettsialpox, Rocky Mountain Spotted Fever, sclerosant therapy, surgical prophylaxis, Syphilis, tick fevers, Typhus fever, UTI.

Don't use for

Class

Tetracycline.