CrCl > 80: 1 g po bid. Take with vitamin C to keep urine pH low.
CrCl < 10:
Important side effects
Important drug interactions
Rants and Screeds
Have to keep the pH < 6 to work. Urea-splitting organisms (Proteus species) will not respond as they prevent urine acidification.
Treatment of choice
UTI, both treatment and prophylaxis.
Don't use for
Turns into formaldehyde in acidic urine.