Infectious Disease Compendium

Mebendazole (Vermox®)

Dosing

CrCl Formula

CrCl > 80: 100 mg po bid to tid, duration of therapy depends on the infecting organism.

CrCl 80-50:

CrCl 50-10:

CrCl < 10:

Hemodialysis:

Peritoneal dialysis:

Important side effects

Constipation, diarrhea, headache, hepatitis (rare), rash, seizures (rare), abdominal pain.

Important drug interactions

Carbamazepine, fosphenytoin, phenytoin.

Rants and Screeds

Pearls

Treatment of choice

Use for

Ancylostoma duodenale, Angiostrongylus cantonensis, Ascaris lumbricoides, Capillaria philippinensis, Dracunculus medinesis, Enterobius vermicularis, Filariasis (Wuchereria bancrofti, Brugia malayi, Brugia timori), Hookworm, Mansonella perstans, pinworm, roundworm, Schistosoma mansoni, Strongyloides stercalis, tapeworm infestation, Toxocara, Necator americanus, Trichuris trichiura, Trichinella spiralis, Trichomonas vaginalis,Visceral larva migrans (alternative), Whipworm.

Don't use for

Class