Infectious Disease Compendium

Honey

Honey. Yes, Honey. And granulated sugar. There is ample evidence that not only is honey good for sterilizing both chronic wounds and burns, it is superior to other modalities (silvadine in particular) for healing (except, probably, a wound vac).

For example, honey kills many bacteria: "With Bacillus subtilis as a test strain, we demonstrated that the variation in bactericidal activity of 11 batches of medical-grade honey was 2-fold. Antibiotic-susceptible and -resistant isolates of Staphylococcus aureus, Staphylococcus epidermidis, Enterococcus faecium, Escherichia coli, Pseudomonas aeruginosa, Enterobacter cloacae, and Klebsiella oxytoca were killed within 24 h by 10%–40% (vol/vol) honey. After 2 days of application of honey, the extent of forearm skin colonization in healthy volunteers was reduced 100-fold, and the numbers of positive skin cultures were reduced by 76% (PubMed)."

Part of the efficacy against bactermia may be to products from Lactic acid bacterial symbionts (PubMed).

Honey also downregulates the mecR1 gene in MRSA, making the beast susceptable to oxacillin (PubMed).

However, use of honey can lead to honey resistance in Pseudomonas (PubMed).

Plus, it is a great opportunity to participate in the naturalistic fallacy.

Honey does not prevent CAPD infections (PubMed).