Infectious Disease Compendium

Famciclovir (Famvir®)

Dosing

from the 2004 PDR

Disease CrCl Dose (mg) Interval (h)
Zoster > 60 500 q 8
40-59 500 q 12
20-39 500 q 24
<20 250 a 24
Hemodialysis 250 after dialysis
Recurrent Genital Herpes > 40 125 q 12
20 - 39 125 q
< 20 125 q 24
HD 125 q 24
Suppression Genital Herpes > 40 250 q 12
20 - 39 125 q 12
< 20 125 q 24
HD 125 after dialysis
Recurrent Disease In HIV > 40 500 q 12
20 - 39 500 q 24
< 20 250 q 24
HD 250 after dialysis

Important side effects

Important drug interactions

Rants and Screeds

Pearls

Treatment of choice

Use for

VZV, Herpes simplex, and Hepatitis B.

Don't use for

Class

Nucleoside analogue.