Infectious Disease Compendium

Ceftizoxime (Cefizox®)

Dosing

CrCl Formula

CrCl > 80: 1 - 3 g q 6 - 8 h iv.

CrCl 80-50: 0.5 - 1.5. g q 8 h iv.

CrCl 50-10: 250 mg - 1 g iv q 24 h iv.

CrCl < 10: 500 mg q 24 h iv.

Hemodialysis: dose after dialysis.

Peritoneal dialysis: 3 g q 48 h iv.

Important side effects

Important drug interactions

Rants and Screeds

Pearls

Treatment of choice

Use for

Arthritis, bacteremia, Cellulitis, Endocarditis, Escherichia coli infections, Gonorrhea, gynecologic infections, Haemophilus influenzae infections, Intra abdominal infections, Klebsiella pneumoniae infections, Meningitis, Osteomyelitis, PID, Pneumonia, Proteus indole positive infections, Providencia stuartii infections, Salpingitis, Sepsis, Serratia infections, surgical prophylaxis, UTI.

Don't use for

Class

Third generation cephalosporin.