Infectious Disease Compendium

Ceftibutin

Dosing

CrCl Formula

CrCl > 80: 200- 400 mg q 12 - 24 h po.

CrCl 80-50: 200 - 400 mg po q 12 -24 h po.

CrCl 50-10: 200 - 400 mg po q 24 h po.

CrCl < 10: 100 mg q 24 h po.

Hemodialysis: 400 mg after dialysis po.

Peritoneal dialysis: 200 mg q 24 h po.

Important side effects

Important drug interactions

Increase in pH will increase absorption.

Rants and Screeds

Pearls

Treatment of choice

Use for

Bronchitis, Diarrhea-bacterial, gynecologic infections, Otitis media, Pharyngitis, Pneumonia, UTI.

Don't use for

Class

Cephalosporin.