Infectious Disease Compendium

Cefpodoxime (Vantin®)

Dosing

CrCl Formula

CrCl > 80: 0.1 - 0.4 g po q 12 h.

CrCl 80-50: 0.1 - 0.4 g po q 12 h.

CrCl 50-10: 0.1 - 0.4 g po q 24 h.

CrCl < 10: 0.1 - 0.4 g po q 24 h.

Hemodialysis: 0.1 -0.4 g po 3x per week.

Peritoneal dialysis:

Important side effects

Important drug interactions

Antacids and H2 blockers will decrease absorption.

Rants and Screeds

Pearls

Treatment of choice

Use for

Bronchitis, Cellulitis, Cystic fibrosis, Gonorrhea, Otitis media, Pharyngitis, Pneumonia, Sinusitis, UTI.

Don't use for

Class

Cephalosporin.