Infectious Disease Compendium

Cefoxitin (Mefoxin®)


CrCl Formula

CrCl > 80: 1-2 gm q 6-8 h iv.

CrCl 80-50: 1-2 gm q 8-12 h iv.

CrCl 50-10: 1-2 gm q 12-24 h iv.

CrCl < 10: 500 mg - 1 gm q 12-48 iv.

Hemodialysis: 1-2 g after hemo.

Peritoneal dialysis:

Important side effects

Important drug interactions

Rants and Screeds


Treatment of choice

Use for

A second generation with reasonable anaerobic coverage. Arthritis, Cellulitis, Diverticulosis/itis, Endometritis, Intra abdominal infections, Osteomyelitis, PID, surgical prophylaxis, UTI.

Don't use for


Second generation cephalosporin.