Infectious Disease Compendium

Cefotaxime (Claforan®)

Dosing

CrCl Formula

CrCl > 80: 500 mg - 2 gm iv q 8 - 12 h.

CrCl 80-50: 500 mg - 2 gm iv q 8 - 12 h.

CrCl 50-10: 500 mg - 2 gm iv q 12 -24 h.

CrCl < 10: 500 mg - 2 gm iv q 24 h.

Hemodialysis: 500 mg - 2 gm after dialysis.

Peritoneal dialysis:

Important side effects

Important drug interactions

Rants and Screeds

Pearls

Treatment of choice

Use for

Anything you would use a third generation cephalosporin for.

Abdominal hysterectomy, Arthritis, Brain abscess, Cellulitis, Endocarditis, Endometritis, Flavobacterium infections, Gonorrhea, Intra abdominal infections, Lyme Disease, Meningitis, Osteomyelitis, PID, Peritonitis, Pneumonia, Salmonella infections, Sepsis, surgical prophylaxis, UTI, ventriculitis.

Don't use for

Class

Third generation cephalosporin.