Infectious Disease Compendium

Cefmetazole

Dosing

CrCl Formula

CrCl > 80: 1 - 2 g iv q 6 - 12 h.

CrCl 80-50: 1 - 2 g iv q 12 h.

CrCl 50-10: 1 - 2 g iv q 16 - 24 h.

CrCl < 10: 1 -2 g iv q 48 h.

Hemodialysis:

Peritoneal dialysis:

Important side effects

Increase in prothrombin time.

Important drug interactions

Rants and Screeds

Pearls

Treatment of choice

Use for

Appendicitis, Cellulitis, Cholangitis, Cholecystitis, chronic Bronchitis, Intra abdominal infections, PID, Peritonitis, Pneumonia, surgical prophylaxis (its main use), UTI.

Don't use for

Class

Second generation cephalosporin.