Infectious Disease Compendium

Carbenicillin

Dosing

CrCl Formula

CrCl > 80: 5-6 gm q 4 h iv.

CrCl 80-50: 5-6 gm q 4 h iv.

CrCl 50-10: 2-3 g q 6 h iv.

CrCl < 10: don't give it.

Hemodialysis: 750 mg - 2 g iv after.

Peritoneal dialysis: 2 g q 6 - 12 h iv.

Important side effects

Important drug interactions

Rants and Screeds

Pearls

Treatment of choice

Use for

Don't use for

Almost a drug of historical interest, it has been superseded by ticarcillin, then mezlocillin, and then pipericillin.

Class

Penicillin.