Infectious Disease Compendium

Anidulofungin (Eraxis®)

Dosing

CrCl Formula

CrCl >Dissiminated candida 200-mg loading dose then by 100 mg daily. Eophageal candidiasis dos100 mg on Day 1,then 50 mg daily.

CrCl 80-50:

CrCl 50-10:

CrCl < 10:

Hemodialysis:

Peritoneal dialysis:

Important side effects

Hypotension, vomiting, headache, constipation, nausea, fever,seizures, and hypokalemia.

Important drug interactions

None.

Rants and Screeds

Pearls

Treatment of choice

Maybe Candida.

Use for

Candida, (maybe) Aspergillus.

Don't use for

Class

Echinocandin.