Infectious Disease Compendium

Amoxicillin

Dosing

CrCl Formula

CrCl > 80: 250-500 mg q 8 h.

CrCl 80-50: 250-500 mg q 8 h.

CrCl 50-10: q 8-12 h.

CrCl < 10: q 12-16 h.

Hemodialysis: 250 mg after HD.

Peritoneal dialysis: Important side effects

Important drug interactions

Rants and Screeds

Pearls

Rash when given for acute mononucleosis is probably more sensitive than a monospot, but less specific.

Treatment of choice

Enterococcus.

Use for

Any Streptococci (all). Actinomyces, Anthrax, bacterial Endocarditis prophylaxis, Borrelia burgdorferi infection (Lyme), bronchiectasis, Bronchitis, Chancroid, Chlamydia infections, COPD exacerbation, Endocarditis, endodontic therapy, prophylaxis, Enteric fever, Neisseria, Haemophilus influenzae, Helicobacter pylori, Leptospira infections, Lyme Disease, Meningitis, Otitis media, periodontal disease, Pharyngitis, Pneumonia, Shigella, Sinusitis acute, Cellulitis, Typhoid fever, UTI, Whipples disease.

Don't use for

Class

Penicillin.