Infectious Disease Compendium

Transfusion Infections

Diagnosis

Depends on the organisms and the donor.

Epidemiologic Risks

Getting blood, either as transfusion or recreational (i.e. IVDA).

Transfusions are immunosuppressive, the more liberal the transfusion, the more hospital acquired infections (PubMed).

Microbiology

Babesiosis, Bacillus spp., Brucella spp., Coagulase-negative Staphylococcus, Cytomegalovirus, E. coli, Ehrlichia, Hepatitis A, Hepatitis B, Hepatitis C, Hepatitis D, HIV, Human T-cell lymphotropic virus, Malaria, any gram-negative rod, Parvovirus B19, Q fever, Relapsing fever, Rocky Mountain spotted fever, Serratia spp, Syphilis, Trypanosoma cruzii, West Nile, Yersinia enterocolitica.

Empiric Therapy

See the specific organism.

Pearls

Risk from a unit of blood (PubMed):

HIV: 1 in 493,000.

HTLV: 1 in 641,000.

HCV: 1 in 103,000.

HBV: 1 in 63,000.

Rants