A wide variety of infections can get the transplant infection. Infection depends on whether it is early or late after the transplant and what the immunosuppression is (prednisone/cyclosporine worse than other immunosuppression regimens). From a practical point of view, they all act like AIDS patients with CD4 <200.
I am going to go out on a limb here and suggest getting a bone marrow transplant. Some infections come in the transplanted organ, some reactivate as a result of immunosuppression in the patient and some are newly acquired .
- Graft vrs Host disease: can mimic infection.
- Cytomegalovirus: can be severe and when causes pneumonia, leads to death. Prophylaxis is part of the care.
- Toxoplasma: especially in the heart and bone marrow transplants patients. Can reactivate in the transplanted heart.
- PML: due to the JC virus, it is a white matter brain melt down.Listeria monocytogenes: usually a meningitis but can present as a febrile non focal illness.
- Post Transplant Lymphoproliferative Disease: Epstein Barr virus caused pseudo-lymphoma, presents with fever and rapidly growing lymph nodes.
- Reactivation local disease and/or dissemination of Tuberculosis, Herpes simplex, Herpes Zoster, Coccidioides immitis, Histoplasma, Penicillium, and Strongyloides stercalis depending on past exposure history.
Except for sepsis, get the diagnostic tests done before you start empiric therapy. Be invasive if you have to; best outcomes are probably with earlier, rather than later, therapy.
Children, do not try this at home, let a professional help you.
Last Update: 05/14/18.