Infectious Disease Compendium

Aphthous ulcers


Look in the mouth. See that painless ulcer? syphilis.

Epidemiologic Risks


Who knows for sure, there are a lot of alleged reasons for idiopathic oral ulcers. Causes of the non-idiopathic variety include herpes, histoplasmosis. If it is painless, think syphilis.

Empiric Therapy

AIDS patients, who can get large apthous ulcers, topical and systemic steroids may be of help as can thalidomide 100-200 mg q.d. for up to six weeks.



ICD9 Codes (Soon to be supplanted by ICD10)

Ulcer 528.2.