Infectious Disease Compendium

Yellow Fever


Flavivirus, one of more than 60.

Epidemiologic Risks

Mosquito bite in sub-Saharan Africa (West > East) and South America (the Amazon basin).


Asymptomatic to non-specific fever to hemorrhagic fever (usually hemorrhagic fever, fulminant hepatic necrosis and renal failure) with a predominant icterus.


Supportive. There is a vaccine, an attenuated virus that produces long-term immunity in greater than 95% of recipients after a single 0.5-mL subcutaneous dose. 2 - 5 days after vaccine, first time vaccinees can get acute MOSF and >50% died. 37 cases worldwide, mostly in older people, maybe 1:20,000 vaccine doses in elderly, about 1:400,000 vaccine in youngerly. So your chance of dying is far greater from the disease than the vaccine.


The vaccine may exacerbate MS.

ICD9 Codes (Soon to be supplanted by ICD10)

yellow fever 060.9.