Infectious Disease Compendium

Orientia tsutsugamushi

Microbiology

In the family rickettsia.

Epidemiologic Risks

Found in South Pacific, Asia, Australia it is spread by a mite from wild rodents. In 2016 it made it to Chiloé Island in southern Chile.

Syndromes

Scrub typhus: Fever, severe headache, and myalgia; often with tender lymphadenopathy in the region of the bite followed in 5 days by rash that goes from extremities.

Treatment

Tetracycline (preferred, better than levofloxicin (PubMed)) or chloramphenicol for 3 to 7 days. In northern Thailand there are tetracycline resistant strains, may want to use ciprofloxacin or azithromycin. And azithromycin is equal to doxycycline (PubMed).

Notes

I just love to say the word "tsutusgamushi"; do not ask me why.