Infectious Disease Compendium

Onchocerca volvulus

Microbiology

A tissue nematode.

Epidemiologic Risks

Sub Sahara Africa. Spread by the black fly.

Syndromes

Onchocerciasis aka River Blindness. Part if not all of the inflammation is due to a bacteria called Wolbachia found in the gut of the worm.

Treatment

Ivermectin 150 microgram/kg once, repeat q 3 to 6 months, although resistance is increasing (PubMed). Moxidectin is in the pipeline for future therapy.

Notes

Good review here (PubMed).