Infectious Disease Compendium

Naegleria

Microbiology

A free living fresh water amoeba. N. fowleri. (PLoS Review)

Epidemiologic Risks

Swimming in fresh water. It runs up the 1st nerve through the cribriform plate and thence into the brain.

It can be found in tap water, including the US (PubMed)

Thanks to global warming, it is now as far north as Minnesota, oh yeah sure doncha know (PubMed).

Washing out your sinus with a Netti pot with tap water is another way to get the bug into your brain (PubMed)(PubMed).

Syndromes

Acute meningoencephalitis.

Treatment

High-dose intravenous and intrathecal amphotericin B. Not that it will work.

Notes

Most die, those who live usually have extensive brain damage. It isn't pretty.