Infectious Disease Compendium



Gram negative diplococcus. M. atlantae, M. catarrhalis, M. lacunata, M. nonliquefaciens, M. osloensis, M. phenylpyruvica.

Epidemiologic Risks

Part of life.


Otitis (20%) (PubMed), sinusitis, URI, exacerbation of COPD (second cause), occasionally pneumonia in patients with COPD. Non catarrhalis spp. only rarely cause infections.


They always make beta-lactamses.

Third generation cephalosporin OR quinolone OR tetracycline OR amoxicillin/clavulanate OR trimethoprim/sulfamethoxisole or azithromycin or clarythromycin or second generation cephlosporin.


The big problem with this organism is 80-90% now make a beta lactamase; probably isn't important in COPD exacerbation; probably is important in pneumonia. Osler died of this organism, or so I have read.