Infectious Disease Compendium

Mansonella

Microbiology

A worm. M. ozzardi, M. perstans, M. streptocerca.

Epidemiologic Risks

Mansonella ozzardi: blackfly and midge bite, in Latin America.

Mansonella perstans: midges in Africa and South America.

Mansonella streptocerca: midge bites in central Africa. Microfilariae can be found on skin bx.

Syndromes

Mansonella ozzardi: most asymptomatic.

Mansonella perstans: most asymptomatic.

Mansonella streptocerca: dermatitis.

Treatment

Mansonella ozzardi:

Mansonella perstans: diethylcarbamazine or albendazole 400 mg bid for at least 1 month. But here is something real cool: to live the Mansonella perstans requires the intracellular endosymbiont (like what got Spiderman and turned his spider suit black) wolbachi. If you treat with doxycycline 200 mg a day for 6 weeks, you get rid of the Mansonella (PubMed).

Mansonella streptocerca: diethylcarbamazine.

Notes

ICD9 Codes (Soon to be supplanted by ICD10)

Mansonella (ozzardi) 125.5.