Infectious Disease Compendium

Exophiala

Microbiology

Fungi, includes E. dermatitidis, E. jeanselmei, E. spinifera and 20 plus others. A black yeast.

Epidemiologic Risks

Found decaying wood and soil.

One outbreak of Exophiala dermatitidis fungemic line infections associated with a product from a compounding pharmacy (PubMed).

Syndromes

Chromomycosis and Madura foot.

A variety of invasive diseases, usually in poor hosts. "18 of 29 known Exophiala species have been proven or were suggested to cause infections in or colonization of humans and animals." (PubMed)

Treatment

Surgery plus ? Posaconazole, Amphotericin, voriconazole and itraconazole have the good MIC's.  Exophiala attenuata is resistant to amphotericin.

Notes

Might be the cause of 'Saxophone Lung' or a hypersensitivity pneumonitis, seen in woodwind instrumentalists (saxophonists, clarinetists, oboists etc.). A saxophone is a woodwind? It has no wood.

Curious Cases

Relevant links to my Medscape blog

Back. In Black

Last update: 05/05/18