Infectious Disease Compendium

Emmonsia

Microbiology

A dimorphic mold (or mould) Emmonsia crescens, Emmonsia parva, Emmonsia pasteuriana.

Related to Blastomyces.

Epidemiologic Risks

E. crescens is found worldwide, E. parva is in North and South America, Eastern Europe, Australia and Asia.

Most cases are in South Africa.  The fungus is worldwide, a rat (and many other mammals) pathogen, that causes Adiaspiromycosis.

In humans usually inhalational.

Syndromes

Occasionally pneumonia.

A disseminated illness in S. Africa. It can look like a widespread folliculitis (PubMed).  Also a case out of India (PubMed).

Treatment

"Recently, the susceptibility of an isolate of E. crescens to various antifungal agents was determined (5). The MICs (in μg/ml) of amphotericin B, itraconazole, voriconazole, caspofungin, fluconazole, and 5-fluorocytosine were 0.06, 0.12 to 0.25, 0.06, 0.5, 64, and 8, respectively, with no significant differences in susceptibilities between the aleurioconidia and adiaspores. Only amphotericin B was fungicidal (PubMed)".

In one case series, amphotericin treatment was most associated with survival (PubMed).

Notes

Can cause a positive urine histoplasma antigen.