Infectious Disease Compendium

Clonorchis sinensis

Microbiology

Liver fluke. Freshwater snails to fish to fish-eating mammals such as humans, dogs, cats, rats, pigs, badgers, weasels, camels, and buffaloes. Camels eat fish? Who knew?

Epidemiologic Risks

Eating raw fish in Asia. Evidently cases are increasing in China (PubMed).

Syndromes

Cholangitis with eosinophilia.

Treatment

Praziquantel 75 mg/kg/day in three doses for 1 day.

Albendazole 10 mg/kg x 7 d may also be used.

400 mg tribendimidine once has less side effects and equal efficacy but is only available in China (PubMed).

Notes

Is also a cause of heptobilary cancer, not the first chronic infection to result in malignancy.

Has been found in Chinese corpses buried in 278 BCE.

Last update: 05/05/18