Infectious Disease Compendium



A chronic skin condition usually of feet after inoculation with fungi; most often in tropical areas. They vary from flat to nodular to warty with draining tracts; progress slowly, biopsy and culture to make the diagnosis.

Epidemiologic Risks

Percutaneous injury, often inadvertent. Usally occurs in them what go barefoot in the dirt. If often festers for years, slowly destroying the limb.


A variety of pigmented fungi:Botryomycoses caespitosus, Cladosporium carrionii, Exophiala spinifera, Exophiala jeanselmei, Fonsecaea pedrosoi, Fonsecaea compacta, Phialophora verrucosa, Rhinocladiella aquaspersa.

Empiric Therapy

Probably itraconazole OR voriconazole for 6 to 12 months. Maybe with 5-FC. Maybe debridement. Some respond to heat such as what pocket warmers provide.



Last update: 05/05/18