Infectious Disease Compendium

Actinobacillus

Microbiology

Includes A. equuli (from animal mouths), A. lignieresi, A. suis, A. ureae. A. actinomycetemcomicans (from human mouth) is now Aggregatibacter actinomycetemcomitans

Syndromes

A. actinomycetemcomicans is a cause of endocarditis (it puts the A in HACEK), head and neck infections and part of aspiration pneumonia with or without empyema. All the rest occasionally cause infections from animal bites.

Treatment

Third generation cephalosporins, ciprofloxacin, gentamicin, tetracyclines. Endocarditis is usually treated with penicillin PLUSan aminoglycoside.

Notes

Sloooooow growers and can take > 48 h to pop positive in blood cultures.