Infectious Disease Compendium

Achromobacter

Microbiology

Achromobacter xylosoxidans (most common human isolate), A. xylosoxidans denitrificans, A. piechaudii, A. ruhlandii, A. insolitus and A. spanius; gram negative rod, a non-fermenter. Some used to be called Alcaligenes.

Epidemiologic Risks

Found in soil and water.

Syndromes

Soft tissue infection after trauma, surgery (isn't that trauma?) and in vasculopaths (most often from a foot ulcer) (PubMed). I love the abstract: "The clinical outcome of the patients was uniformly good after antibiotic treatment, except in 4 patients who suffered recurrence of the infection." So it wasn't uniformly good, now was it?

Bacteremia and other nosocomial infections in the immunoincompetent, increasingly reported in cystic fibrosis.

Treatment

Carbapenems, antipseudomonal penicillins (piperacillin), and trimethoprim/sulfamethoxazole. Resistance to ciprofloxacin, levofloxacin, aminoglycosides, and monobactams are common.

Notes

Curious Cases

Relevant links to my Medscape blog

UnWell

Last update: 05/05/18