Infectious Disease Compendium

Absidia

Microbiology

A mould, in family Mucoraceae, an agent of mucormycosis. Includes A. corymbifera (most common clinical isolate) as well as Absidia coerulea, Absidia cylindrospora, Absidia glauca, Absidi. ramosa, and Absidia spinosa.

Epidemiologic Risks

Syndromes

Invasive disease in the neutropenic, especially leukemic. Lung, CNS, rhinocerebral and cutaneous lead the list.

Treatment

Amphotericin B, at high dose (1.5 mg/kg/d is a good start) but it is as effective as I would be in the ring with Mike Tyson. It is resistant to caspofungin, voriconazole, fluconazole and itraconazole in vivo (PubMed).

Notes

Barely susceptible to anything, it is best treated with resection if possible and reconstitution of the host immune system.

ICD9 Codes (Soon to be supplanted by ICD10)

Absidia 117.7.